New Test Reveals Antibiotic-Resistant Bacteria in 30 Minutes

Shared by Radhika Narayanan | 6 4 0 | about 2 months ago

New Test Reveals Antibiotic-Resistant Bacteria in 30 Minutes

Researchers at Caltech have developed a new rapid test for antibiotic-resistant bacteria, which can give results within 30 minutes.Antibiotics are becoming less effective with the rise of multi-drug resistant strains of bacteria. At present, a doctor doesnt know if their patient is infected with a drug-resistant strain without sending a sample to a lab, and it can take as long as three days to get the results back.This means that most antibiotic treatments are a shot in the dark. A new test, developed by Caltech researchers, could help change this. The research team aimed to develop a simple test that could be completed during a short visit to a doctors surgery.The researchers focused on urinary tract infections (UTIs), which are very common, and developed a rapid test that works on the following principle. A doctor would divide a urine sample from a patient with a UTI into two parts, and expose one part to an antibiotic for 15 minutes, while not treating the other part.The bacteria in each sample are then broken apart and their cellular contents are analyzed through a chemical detection process called digital real-time loop-mediated isothermal amplification. This technique amplifies specific DNA markers on a chip, allowing doctors to visualize them in the samples, where they appear as fluorescent spots.

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Categories Medtech & Devices

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